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This allows Smugglers Share to draw you an obscene amount of cards if everyone is drawing more than one card each turn
It made it difficult for decks that wanted to specifically combat mono-red to attack it appropriately, since Nemesis would roadblock actual combat, or even lifegain strategies that should be good against it
Let me know in the comments or over on the Draftsim Discord
There are a sad selection of combos that simply don't translate into cube because there isn't enough redundancy in the parts
"OP03-047 Zeff", which can send cards to your trash while also clearing the board, has excellent synergy with these cards