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GP000100: MUC1(126-149)-STn(130,131) Pack Size:0.5 mg Fmoc-L-Ser((Ac)7-Mel-β-D)-OH

SKU: 74353362167
4.2
USD350.00 USD382.00

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Ships within 48 hours · Estimated delivery Aug 16 - Aug 21

Description

Fmoc-L-Ser((Ac)7-Mel-β-D)-OH

The terminal amine is protected with a tert-butyloxycarbonyl (Boc) group

mimicking the inner N-glycan substructure released by endo-β-mannosidase activity

TF Epitope (Threonine)

a Ser/Thr modification of EGF-like and thrombospondin repeats relevant to Notch signaling

GP000100: MUC1(126-149)-STn(130,131) Pack Size:0.5 mg Fmoc-L-Ser((Ac)7-Mel-β-D)-OHC133H209N33O58 3198. 27 MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Pro126 Gly149; UniProt position 126 149, aa length 24) from the variable number tandem repeat (TR) domain. The fragment contains tumour associated carbohydrate antigen (TACA), Sialyl Tn or STn (Neu5Ac2 6GalNAc O Ser) at Ser130 and Neu5Ac2 6GalNAc O Thr at Thr131. The C terminus is carboxylic acid. MUC1(126 149) STn(130,131) Mucin1; Synthetic MUC 1 (di STn) glycopeptide

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