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Fmoc-Thr(β-D-Glc)-OH
/ β-D-Gal-Butyl-Carboxylic Acid / β-Gal-Bu-CO2H
supplied as the disodium salt
Fmoc-Ser([Galβ(1-4)Glc](Ac)7)-OH
producing high-avidity binding that substantially exceeds the affinity of monovalent GalNAc ligands and closely mimics the geometry of clinically validated Tri-GalNAc targeting moieties used in approved GalNAc-siRNA therapeutics
GP100110: Arg8-CGSG-MUC1(137-156)-Tn(144) Pack Size:0.5 mg Fmoc-Thr(β-D-Glc)-OHC146H253N63O45S 3643. 03 MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Gly137 His156; UniProt position 137 156, aa length 20) from the variable number tandem repeat (TR) domain. The fragment contains tumour associated carbohydrate antigen (TACA), Tn (GalNAc O Thr) at Thr144. Arg8 is conjugated at N terminal. Arg8 is separated from the MUC1 sequence by Cys Gly Ser Gly. The C terminus is an amide. Arg8 CGSG MUC1(137 156) Tn(144) Mucin1; R8
