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PE634005: α-Man-PEG3-Azide (Peracetate) label-new / α-D-Man-Propyl-Azide / α-Man-Pr-N3

SKU: 46774792024
4.9
EUR200.00 EUR233.00

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Description

/ α-D-Man-Propyl-Azide / α-Man-Pr-N3

The fragment contains tumour-associated carbohydrate antigen (TACA)

Adenuric-d9

while the free α-carboxylic acid is available for coupling to the growing resin-bound peptide

2-[2-(2-Mercaptoethoxy)ethoxy]ethyl 2-acetamido-2-deoxy-β-D-lactoside

PE634005: α-Man-PEG3-Azide (Peracetate) label-new / α-D-Man-Propyl-Azide / α-Man-Pr-N3C20H31N3O12 505. 47 A peracetylated D mannose ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. The sugar hydroxyls are acetate protected to increase lipophilicity for cell membrane permeability. This compound provides an D

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