GA731000: Fmoc-Thr((Ac)3-Fuc-α-L)-OH Pack Size:25 mg 6)-tri-O-acetyl-β-D-glucopyranosyl)-L-serine

6)-tri-O-acetyl-β-D-glucopyranosyl)-L-serine

32 / A β-D-N-acetylglucosamine (GlcNAcβ) ligand equipped with a terminal carboxylic acid through a short butyl spacer

and mechanism of action studies

32 / A synthetic heparan sulfate (HS) / heparin disaccharide bearing iduronic acid (IdoA) linked to 2-N-sulfated glucosamine (GlcNS)

N-α-Fmoc-O-(2

GA731000: Fmoc-Thr((Ac)3-Fuc-α-L)-OH Pack Size:25 mg 6)-tri-O-acetyl-β-D-glucopyranosyl)-L-serineC31H35NO12 613. 61 An Fmoc protected L threonine building block carrying an L fucose residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as three acetate esters (Ac3), which keep the glycan inert